Friday, February 7, 2014

New research suggests that vitamin C might make cancer drugs more effective. But past discredited claims about the vitamin's effectiveness in treating cancer are likely to hinder further study.

Promising cancer therapy treatment: Vitamin C


Studies examine vitamin C
Ovarian cancer patients involved in a study were given 75 to 105 grams of vitamin C depending on their body weight. A typical orange has about 50 milligrams of vitamin C. (Bill Hogan / Chicago Tribune / January 21, 2010)


Scientists have identified a simple, inexpensive compound that made cancer drugs more effective in mice and helped human patients weather the toxic side effects of chemotherapy.
But even as they touted their experimental results, they acknowledged that their remedy was unlikely to inspire the vigorous — and expensive — research necessary to win regulatory approval and join the ranks of mainstream medicine.
The drug in question is vitamin C. When absorbed from foods such as oranges, strawberries, broccoli and kale, it feeds neurotransmitters and helps the body make collagen, among other important functions. It has also gained a cult following as an alternative form of cancer treatment thanks to Linus Pauling, a two-time winner of the Nobel Prize.
Pauling's contention that large doses of vitamin C could prevent and treat most cancers could not be supported by clinical trials. His discredited claims shut down research for decades, said Dr. Jeanne Drisko, director of integrative medicine at the University of Kansas Medical Center.
"There's been a bias since the late 1970s that vitamin C cancer treatment is worthless and a waste of time," said Drisko, a member of the team that published the new results Wednesday in the journal Science Translational Medicine. Now, she said, "we're overcoming that old bias."


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